Bioinformatics is an interdisciplinary research field that studies biological phenomena using approaches from computer science, applied mathematics, and statistics. Due to the extensive usage and ongoing development of high-throughput sequencing (HTS) technologies, also known as next-generation sequencing, the term is now becoming prevalent in many study domains in microbiology. Because of their ability to sequence the entire genome in a single step, these methods are often referred to as whole genome sequencing (WGS). In the following years, the discipline of computational microbiology will continue to expand fast.
The exponential rise in computer speed and memory storage capacity has ushered in a new era in biological data analysis. Hundreds of microbial genomes and many eukaryotic genomes have been sequenced, including a clearer version of the human genome, raising hopes for better microbe control. The objectives are ambitious, including the development of rational drugs and antimicrobial agents, the development of new enhanced bacterial strains for bioremediation and pollution control, the development of better and easier-to-administer vaccines, the development of protein biomarkers for various bacterial diseases, and a better understanding of the host-bacterium interaction to prevent bacterial infections.