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Speaker at  and Expo on Applied Microbiology 2023 - Yibeltal Aschale
Debre Markos University, Ethiopia
Title : The prevalence, antibiotic susceptibility pattern and associated factors of bacterial vaginosis among women of reproductive age group in felegehiwot referral hospital, Ethiopia

Abstract:

Background: Bacterial vaginosis is an infection of the vagina, which results due to change in the normal balance of vaginal bacteria. The aim of this study was to assess the magnitude and determinants of bacterial vaginosis among women of reproductive age group in Felege Hiwot Referral Hospital, Ethiopia

Materials and Methods: A cross-sectional study was conducted among women during the reproductive period at Felege Hiwot Referral Hospital, Ethiopia from September 2019 to October 2020. About 413 vaginal swab samples were collected and examined using the Nugent scoring system and culture. Data were analyzed by SPSS version 25. The odds ratio (OR) was used as a measure of the strength of association and reported with 95% confidence intervals. P-value ≤ 0.05 was considered to be statistically significant. Bivariate and multivariate logistic regression models were used to identify possible associated factors with bacteria causing bacterial vaginosis.

Results: The overall prevalence of bacteria causing bacterial vaginosis was 39.5%. The predominant bacteria were S. aureus (25.4%), G. vaginalis (22.7%), S. agalactiae (14.1%), and E. coli (13.5%). S. aureus was resistant to erythromycin (69.8%) and trimethoprim/ sulfamethoxazole (53.5%); despite this, it was susceptible to ciprofloxacillin (93%), gentamycin (93%), and cefoxitin (90.7%). On the other hand, E. coli was resistant to trimethoprim/sulfamethoxazole (91.3%) and ceftriaxone (63.6%), but was susceptible to ciprofloxacillin (95.5%) and gentamycin (93%).

Conclusion: The high prevalence of bacterial vaginosis was significantly associated with the pH level of the vagina (≥4.5), participant age (≤20), pregnancy, and history of HIV infection. Therefore, early identification of factors leading to bacterial overgrowth on the vagina is very important to protect maternal and child morbidity and mortality.

Audience Take Away

  • The magnitude of bacterial vaginosis among reproductive age group women.
  • The susceptibility pattern of antibiotics.
  • Determinant factors of bacterial vaginosis.

Biography:

Yibeltal Aschale studied Medical Laboratory Science at University of Gondar, Ethiopia and graduated as BSc in 2010. He then employed at College of Health Science, Debre Markos University, Ethiopia as Assistant lecturer. He then rejoined University of Gondar, Ethiopia and received his MSc degree in Medical Parasitology in 2017. After three years of participations in teaching and research, he obtained the position of Assistant Professor at Debre Markos University, Ethiopia in 2021. He has published more than 20 research articles in peer reviewed reputable journals.

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